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Pet Vaccination Schedules Explained: What Shots Your Dog or Cat Really Needs

June 1 2025

Vaccines are one of the simplest, most effective ways to protect your pet’s health. They help prevent life-threatening illnesses, reduce the spread of disease, and can even protect people in your household from zoonotic infections, such as rabies, which is actually the deadliest disease in the world. But pet owners often wonder: What vaccines are truly necessary? How often should they be given? And are indoor pets at risk too? This guide from a Severn, MD vet will break down everything you need to know about pet vaccination schedules, so you can make informed decisions about your pet’s care.

Core vs. Non-Core Vaccines

Veterinarians divide pet vaccines into two main categories: core and non-core. Core vaccines are considered essential for all pets, regardless of lifestyle. These vaccines protect against highly contagious, potentially fatal diseases. Non-core vaccines are optional and based on a pet’s risk factors, such as exposure to other animals, geographic location, and specific health conditions.

For dogs, core vaccines include:

  • Canine distemper
  • Parvovirus
  • Adenovirus (hepatitis)
  • Rabies

Non-core vaccines may include:

  • Bordetella (kennel cough)
  • Leptospirosis
  • Lyme disease
  • Canine influenza

For cats, core vaccines include:

  • Feline panleukopenia (distemper)
  • Herpesvirus
  • Calicivirus
  • Rabies

Non-core options for cats:

  • Feline leukemia virus (FeLV)
  • Bordetella
  • Chlamydophila felis

Vaccination Timeline: Puppies and Kittens

Young animals are especially vulnerable to disease, which is why timely vaccination is critical during the first few months of life. Puppies and kittens typically start their vaccines around 6 to 8 weeks of age, with boosters every 3 to 4 weeks until about 16 weeks old.

Here’s a sample timeline for a puppy:

  • 6–8 weeks: First round of DHPP (Distemper, Hepatitis, Parvovirus, Parainfluenza)
  • 10–12 weeks: Second DHPP + Bordetella
  • 14–16 weeks: Final DHPP + Rabies
  • Optional based on lifestyle: Leptospirosis, Lyme, Canine influenza

And for a kitten:

  • 6–8 weeks: First round of FVRCP (Feline Viral Rhinotracheitis, Calicivirus, Panleukopenia)
  • 10–12 weeks: Second FVRCP + FeLV (if needed)
  • 14–16 weeks: Final FVRCP + Rabies

Vaccinations often need to be completed in a series to build full immunity. Skipping boosters or delaying shots can leave your pet unprotected.

Adult Pet Vaccine Schedule

After the initial puppy or kitten series, adult pets move to a maintenance schedule. Some vaccines are given annually, while others may be effective for up to three years.

For dogs, this generally includes:

  • DHPP: every 1 to 3 years
  • Rabies: every 1 to 3 years (as required by law)
  • Bordetella: annually or before boarding
  • Leptospirosis: annually if at risk

For cats, the adult vaccine plan includes:

  • FVRCP: every 1 to 3 years
  • Rabies: every 1 to 3 years
  • FeLV: annually if outdoor or multi-cat household

This is just an estimate. You’ll want to get specific recommendations. Your Severn, MD veterinarian will assess your pet’s health and needs, and will determine the right timing and combinations.

Why Indoor Pets Still Need Vaccines

A common misconception is that indoor-only pets don’t need vaccines. But even indoor pets face exposure risks. Viruses and bacteria can enter your home via shoes, other pets, open windows, or trips to the groomer or vet. The rabies vaccine, in particular, is legally required in many areas—even for indoor cats. That’s because the disease, as mentioned above, is extremely dangerous. It has a whopping 99% mortality rate.

Additionally, if an emergency arises and your pet needs to be boarded or hospitalized, proof of up-to-date vaccinations may be mandatory. Keeping your pet vaccinated ensures they’re ready for any situation.

Vaccine Safety and Side Effects

Modern vaccines are rigorously tested for safety and are generally well tolerated. Side effects, if any, are usually mild and temporary. These may include:

  • Soreness at the injection site
  • Mild lethargy or fever
  • Decreased appetite for 24–48 hours

Serious reactions are rare, but signs of reactions, such as facial swelling, vomiting, hives, or difficulty breathing do happen on occasion. Pets that show these symptoms require immediate veterinary attention. Your vet can adjust your pet’s vaccination plan if a reaction occurs.

Customizing the Schedule for Your Pet

Not every pet needs every vaccine. That’s why working with your veterinarian to create a customized vaccination plan is important. Factors to consider include:

  • Age and breed
  • Travel habits
  • Boarding or daycare attendance
  • Outdoor exposure
  • Health history or chronic conditions

A tailored plan ensures your pet is fully protected without over-vaccinating, which can reduce stress on their immune system and minimize potential risks.

FAQs About Pet Vaccines

  • Can my pet skip a vaccine if they’ve had a reaction in the past? Possibly. Your vet may recommend alternatives or a modified schedule, depending on the severity of the reaction.
  • Are titer tests a good alternative to vaccines? In some cases, yes. A titer measures immunity levels and may be used to determine if revaccination is necessary.
  • Can vaccines be given during a sick visit? Typically, it’s best to wait until your pet is healthy to ensure the immune system can respond properly.

Final Thoughts: Vaccinations Are Lifesavers

Staying up to date with your pet’s vaccinations is one of the most effective ways to keep them healthy. With so many diseases preventable by simple shots, skipping vaccines is a risk not worth taking. A consistent vaccination schedule can extend your pet’s life, prevent painful illnesses, and keep your household safe.

Contact Our Glen Burnie MD Animal Clinic

Is your pet up to date on their vaccines? Schedule a wellness exam today and let our team help you create a customized vaccine schedule that fits your pet’s needs.

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